Burden‐of‐illness vaccine efficacy

Epidemiological assessment of vaccine efficacy

The success of an epidemiological program against infectious diseases depends on an effective prophylactic vaccine. Although efficacy and effectiveness are used interchangeably, effectiveness depends upon efficacy. Few methods are in use to assess the efficacy of the vaccine, a randomized double blind controlled trial is the least ambiguous method for evaluation. Observational designs for vacci...

Efficacy of thermostable I-2 Newcastle disease vaccine compared to B1 commercial vaccine in broiler chicken

Frequent vaccination failures have occurred in the broiler farms in Eurasian countries during Newcastle disease outbreaks. The disease is enzootic in many countries of the region, especially in southwest Asia. I-2 vaccine has been used successfully in village chickens in many Asian and African countries. Our preliminary study showed good efficacy of the vaccine in broiler chickens. Therefore th...

Efficacy of Experimental Inactivated Vaccine for Infectious Bronchitis Disease

The efficacy of inactivated oil-emulsion H9N2 avian influenza vaccine

An experimental inactivated oil-emulsion H9N2 avian influenza vaccine was formulated with 3 parts ofinactivated avian influenza antigen A/Chicken/Iran/101/1998(H9N2) emulsified in 7 parts of oil adjuvant.Twelve week-old specific pathogen-free (SPF) chickens were divided into seven groups of 10 birds. Sixgroups were vaccinated with 1, 1/10th, 1/50th, 1/100th, 1/200th and 1/400th field dose of th...

ANTHRAX VACCINE Safety and Efficacy Issues